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Moments like this are typical of Cox's experience as he scours
the world's flora in search of plants that will benefit Western
medicine. Cox has spent years in Samoa interviewing or
apprenticing himself to traditional healers. He has also
traveled throughout the South Pacific, as well as in Southeast
Asia, South America, East Africa and as far north as Sweden's
Lapland. In Samoa alone, healers have led him and his colleagues
to 74 medicinal plants that might prove useful.
Samoan healers concoct poultices and infusions from the leaves,
bark and roots of local plants, using them for conditions that
range from high fever to appendicitis. Among them are root of
'Ago (Curcuma longa) for rashes, leaves of the kuava tree
(Psidium guajava) for diarrhea, and the bark of vavae (Ceiba
pentandra) for asthma. Virtually all the healers are women who
learned their art from their mothers, who in turn learned it
from their mothers. Now knowledge of the recipes and their
administration, even the location of the plants in the forests,
is endangered as more and more daughters forgo the long filial
apprenticeships in favor of using Western pills and ointments.
For this reason, the discovery of young practicing healers like
Salome delights Cox, who believes that only people like her can
prevent the loss of centuries of knowledge. If he can carry
Salome's knowledge to the developed world in the form of plants
whose myriad chemical compounds might help combat incurable
diseases--notably cancer, aids and Alzheimer's--the impetus to
save the Samoan rain forest, and all forests, will be that much
stronger.
Fewer than 1% of the world's 265,000 flowering plants, most
inhabiting equatorial regions, have been tested for their
effectiveness against disease. "We haven't even scratched the
surface--not even in our own backyard," says Jim Miller,
director of the Missouri Botanical Garden's natural-products
program. Yet nearly a quarter of prescription drugs sold in the
U.S. are based on chemicals from just 40 plant species. Examples
are abundant. Codeine and morphine are derived from poppies.
Vincristine and vinblastine, isolated from the rosy periwinkle,
help treat cancers, including Hodgkin's disease and some
leukemias. Curare, taken from several lethal Amazonian plants
and often used to tip hunting arrows, is used in drugs that
bolster anesthesia. An extract of the snakeroot plant,
reserpine, traditionally employed in Asia to counteract
poisonous snake bite, is the basis of a number of tranquilizers
and hypertension drugs. Taxol, a compound in the bark of the
Pacific yew, is used to treat some cases of advanced ovarian and
breast cancer.
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